Murine Cardiac Vector-Flow Imaging with High-Frequency 2D Row-Column CMUT Arrays
The proposed research will be conducted in the Department of Biomedical Engineering at NC State University (NCSU).
The goal of this project is to investigate the feasibility of using high-speed, high-frequency ultrasound to characterize the complex blood flow patterns in an aortic banding mouse model of hypertrophy. A research ultrasound platform and 30-MHz transducers with 100-um lateral resolution and 2-cm penetration depth will be used for sub-ms, full-frame quantitative data collection. Novel row-column addressed high frequency 2D CMUT transducer arrays will also be developed. This research will take place in the Department of Biomedical Engineering at NC State.
Sponsor
Cornell University
The grant—running from September 1, 2022 to August 31, 2026—is for a total of $194,783.
Principle Investigators
Omer Oralkan
Feysel Yalcin Yamaner
More Details
The overall goal of this project is to establish feasibility of using high-speed, high-frequency-ultrasound, plane-wave Doppler vector-flow methods to characterize the complex blood flow patterns in an aortic banding mouse (ABM) model of hypertrophy which develop gradual heart failure due to chronic left ventricle pressure overload. A research ultrasound platform and 30-MHz ultrasound transducers with 100-um lateral resolution and 2-cm penetration depth will be used for the proposed studies to achieve sub-ms, full-frame quantitative data. We will develop the novel row-column addressed high frequency 2D CMUT transducer arrays for the proposed studies.