Cranos Williams
He/Him/His
Biography
Research Interests: I am currently the director of the EnBiSys Research Laboratory. The EnBiSys Lab is a highly collaborative, multidisciplinary research laboratory, focused on the development of targeted computational and analytical solutions for modeling and controlling biological systems. The solutions we develop are used to build and strengthen the transition from large-scale high-throughput –omics data to highly connected kinetic models in the post-genomic era; models that can be used to attain the depth, understanding, and comprehension needed to manipulate and control biological systems for a defined purpose.
Specific interests in this field include:
- Nonlinear Systems Analysis
- System Identification
- Uncertainty Analysis
- Optimal Experimental Design
- Biological Signal and Data Processing
Patents: S. Chen, L. Ray, N. Cahill, M. Goodgame, and C. Williams, “Method of Image Registration using Mutual Information,” U.S. Patent 7,263,243, Aug. 28, 2007.
Education
-
Ph.D.
2008
Electrical Engineering
North Carolina State University, Raleigh -
Master's
2002
Electrical Engineering
North Carolina State University, Raleigh -
Bachelor's
2001
Electrical Engineering
NC A&T State University, Greensboro
Research Focus
Recent Publications
- Compositionality, sparsity, spurious heterogeneity, and other data-driven challenges for machine learning algorithms within plant microbiome studies (2023)
- FER and LecRK show haplotype-dependent cold-responsiveness and mediate freezing tolerance in Lotus japonicus (2023)
- Dynamics of BMP signaling in the earlyDrosophilaembryo (2022)
- Identification of Transcription Factors Regulating SARS-CoV-2 Tropism Factor Expression by Inferring Cell-Type-Specific Transcriptional Regulatory Networks in Human Lungs (2022)
- POPEYE intercellular localization mediates cell-specific iron deficiency responses (2022)
- Practical spectral photography II: snapshot spectral imaging using linear retarders and microgrid polarization cameras (2022)
- A multiscale model of lignin biosynthesis for predicting bioenergy traits in Populus trichocarpa (2021)
- Computer vision approach to characterize size and shape phenotypes of horticultural crops using high-throughput imagery (2021)
- Enzyme Complexes of Ptr4CL and PtrHCT Modulate Co-enzyme A Ligation of Hydroxycinnamic Acids for Monolignol Biosynthesis in Populus trichocarpa (2021)
- High-throughput image segmentation and machine learning approaches in the plant sciences across multiple scales (2021)
Highlighted Awards
Awards & Honors
- 2021 - Alumni Association Outstanding Research Award, Induction into Research Leadership Academy
- 2019 - Selected for National Academy of Engineering, Frontiers of Engineering Symposium
- 2019 - Alcoa Foundation Research Achievement Award
- 2013 - ECE William F. Lane Teaching Award
- 2009-2010 - Faculty Research and Professional Development Award
- 2003-2008 - National Science Foundation Graduate Research Fellowship
Recent News

Faculty Making a Lasting Impact
Posted on December 27, 2022 | Filed Under: Faculty and News
The students of Dr. Winser Alexander have created the WEA Endowment Committee to honor Alexander’s legacy during his time at NC State.

Cranos Williams Named Goodnight Distinguished Professor
Posted on March 23, 2022 | Filed Under: Faculty
NC State faculty member Cranos Williams was recently named a Goodnight Distinguished Professor in Agricultural Analytics by the College of Engineering and CALS.

Introducing NC State’s Newest Outstanding Researchers
Posted on March 16, 2021 | Filed Under: Awards
Congratulations to Cranos Williams, recipient of the 2021 Outstanding Research Award for his interdisciplinary research and teaching.
Media Mentions

Computational tool offers new insight into key biological processes
March 10, 2014
NC State researchers have developed a computational tool designed to guide future research on biochemical pathways that govern a host of biological processes. Cranos Williams, electrical and computer engineering, featured.